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助理教授,研究员,博士生导师
电子邮箱:lifengzhou@pku.edu.cn
工作经历:
2023.03至今:2138cn太阳集团古天乐,澳门太阳娱乐网站官网先进制造与机器人系系,助理教授、研究员、博士生导师
2021.07至2023.02:伊利诺伊大学厄巴纳香槟分校(University of Illinois Urbana-Champaign),Carl R. Woese Institute for Genomic Biology 与Nick Holonyak, Jr. Micro And Nanotechnology Laboratory,IGB Fellow博士后(合作导师:Brian T. Cunningham 与 Xing Wang教授)
2017.07至2021.06:纽约州立大学奥尔巴尼分校RNA研究所(The RNA Institute at State University of New York at Albany)博士后(合作导师:Ken Halverson博士)
教育经历:
2012.08至2017.05:俄亥俄州立大学 (The Ohio State University) ,机械与航空航天工程系,博士(导师:Hai-jun Su与Carlos E. Castro教授)
2009.09至2012.03:北京邮电大学,机械设计及理论,硕士(导师:廖启征与魏世民教授)
2005.09至2009.06:北京邮电大学,机械工程及自动化,学士
研究领域:
机构学、机器人学、柔顺机构、微纳机器人、DNA折纸及生物医学应用。采用核酸分子(DNA与RNA)为材料,结合现代机械设计理论,探索制造拥有多自由度、复杂构型变化与特殊机械性能的纳米机器与机器人,开发相关的分析算法、测试仪器、控制方法与实验制造平台。探索核酸纳米机器在微纳制造、精准诊断与靶向载药中的应用。
研究成果:
近年来,在Science Advances、Cell Reports Methods、Small、Mechanisms and Machine Theory、ASME Journal of Mechanisms and Robotics等主流期刊上发表论文20余篇。研究成果受到了国际同行广泛的关注,被Science, Xinhuanet.com等多家媒体报道。
招聘信息:
课题组长期招收硕士/博士研究生、博士后,欢迎对宏观与微观机器人、核酸纳米技术与应用感兴趣的本科生加入并参与科研活动。
学术服务:
受邀为十余个国际知名期刊的审稿人,包括Nature Communications、Mechanisms and Machine Theory、ASME Journal of Mechanisms and Robotics、ASME Journal of Mechanical Design等。
部分论文列表:

(*通讯作者):

1.  Zhou, L., “DNA Mechanisms and Machines for Nanorobotics,” invited book chapter for “Encyclopedia of Robotics”, Springer, 2021, Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-41610-1_217-1

2.  Xiong, Y., Huang, Q., Canady, T. D., Barya, P., Liu, S., Arogundade, O. H., Race, C. M., Che, C., Wang, X., Zhou, L., Wang, X., Kohli, M., Smith, A. M., and Cunningham, B. T., 2022, “Photonic Crystal Enhanced Fluorescence Emission and Blinking Suppression for Single Quantum Dot Digital Resolution Biosensing,” Nat Commun, 13(1), p. 4647.

3.  Zhou, L., Hayden, A., Chandrasekaran, A. R., Vilcapoma, J., Cavaliere, C., Dey, P., Mao, S., Sheng, J., Dey, B. K., Rangan, P., and Halvorsen, K., 2021 “Sequence-selective purification of biological RNAs using DNA nanoswitches,” Cell Reports Methods. 1(8), p. 100126 (Cover Article)

4.  Zhou, L.*, Valsangkar V. A., Yan, M., Chandrasekaran, R. A., Feldblyum, J. I., R., Sheng, J., and Halvorsen, K.*, 2021, “A mini DNA-RNA Hybrid Origami Nanobrick,” Nanoscale Advances, D1NA00026H,

5.  Punnoose, J. A., Hayden, A., Zhou, L., and Halvorsen, K., 2020, “A Wi-Fi Live Streaming Centrifuge Force Microscope for Benchtop Single-Molecule Experiments,” Biophysical Journal, 119(11), p. 2231-2239.

6.  Zhou, L.; Chandrasekaran, A. R.; Punnoose, J. A.; Bonenfant, G.; Charles, S.; Levchenko, O.; Badu, P.; Cavaliere, C.; Pager, C. T.; Halvorsen, K. Programmable Low-Cost DNA-Based Platform for Viral RNA Detection. Science Advances 2020, eabc6246.

7.  Zhou, L., Marras, A. E., Huang, C.-M., Castro, C. E., and Su, H.-J., 2018, “Paper Origami-Inspired Design and Actuation of DNA Nanomachines with Complex Motions,” Small, 14(47), p. e1802580.

8.  Lei, D., Marras, A. E., Liu, J., Huang, C.-M., Zhou, L., Castro, C. E., Su, H.-J., and Ren, G., 2018, “Three-Dimensional Structural Dynamics of DNA Origami Bennett Linkages Using Individual-Particle Electron Tomography,” Nat. Commun., 9(1), p. 592.

9.  Zhou, L., Su, H.-J., Marras, A. E., Huang, C.-M., and Castro, C. E., 2016, “Projection kinematic analysis of DNA origami mechanisms based on a two-dimensional TEM image,” Mech. Mach. Theory, 109, pp. 22–38.

10.Zhou L., Marras A. E., Castro, CE, Su, H., 2016, “Pseudorigid-Body Models of Compliant DNA Origami Mechanisms”. ASME. J. Mechanisms Robotics, 8(5):051013-051013-11. doi:10.1115/1.4032213.

11.Zhou, L., Marras, A. E., Su, H.-J, and Castro, C. E., 2015, “Direct design of an energy landscape with bistable DNA origami mechanisms,” Nano Lett., 15 (3), pp. 1815–1821.

12.Marras, A. E., Zhou, L., Su, H.-J., and Castro, C. E., 2015, “Programmable motion of DNA origami mechanisms,” Proc. Natl. Acad. Sci., 112, pp. 713–718.

13.Zhou, L., Marras, A. E., Su, H.-J., and Castro, C. E., 2013, “DNA Origami Compliant Nanostructures with Tunable Mechanical Properties,” ACS nano, 8, pp. 27–34.