讲座题目：Gene Targeting and Biocore Technology in Biomedical Research 

报告人：Li Yang

时 间：6月8日（周三）上午8：30
地 点：校医院A534会议室
主持人：葛子钢（特聘研究员）

报告内容摘要：
     The effect of the absence of a gene can be very informative about the normal function of the gene. A gene knockout (KO) is a genetic technique in which one of an organism’s genes is made inoperative. Knockout animals can be produced by a technique called gene targeting. This is the replacement of one gene sequence, the sequence resident in the mouse genome, with a related sequence that has been modified in the laboratory to contain a mutation. An overview and the use of this technology will be discussed.
     To better understand biomolecular interactions, cutting-edge biosensors are revolutionizing and are established as routine biophysical tools in research laboratories worldwide. Biacore systems are used in areas such as pharmaceutical drug discovery, antibody characterization, proteomics, immunogenicity, biotherapeutic development and manufacture. An introduction for basic principle and some application will be discussed.