报告内容摘要

Heart disease in children occurs in close to 1% of all live births and is responsible for continued morbidity and mortality in the pediatric population.  The group of patients with “single entricle physiology” are an especially challenging group of patients who undergo a number of palliative surgeries in an attempt to prolong life and result in an acceptable physiologic arrangement.  The final surgical procedure is typically the Fontan operation, resulting in separation of the oxygenated and deoxygenated circulations.   Unfortunately, the long term outcomes for these patients remains poor, and by the teenage years, a number of complications develop that can lead to premature death or heart transplantation.   Research at our institution has utilized MRI data, in-vitro modeling, computer modeling and animal models to modify surgical procedures and develop novel conduits for these patients.  In addition, valve placement within the Fontan circulation has been investigated in our labs as a potential improved flow to decrease energy loss and improve flow.  The details of this research will be discussed.  

报告人简介

Co-Director, Center for Pediatric Innovation

Associate Director, Atlanta Pediatric Device Consortium

Emory University Department of Pediatrics

Chief Research Officer, Children’s Healthcare of Atlanta

Atlanta, GA USA