报告内容摘要

Current treatments for severe heart valve diseases are either whole valve replacement or valve repair, through either open-heart surgery or more recent transcatheter valve intervention. Although the past two decades have seen major advances in valvular disease diagnostics, improvement in interventional cardiology, surgical techniques and prosthetic valve devices, heart valve disease continues to be a significant cause of morbidity and mortality and its prevalence is increasing with the aging population.  To better understand the natural history of valve disease and improve patient outcomes, an intense area of research has been focused on understanding the heart valve function at multi-scale levels.  In this talk, we will focus on the image- and biomechanics-based techniques for realistic modeling of cardiac valve function and intervention. Specifically, we will discuss the integration of 3D reconstructed patient valve geometries and valve material properties into computational models of cardiac valves.  We will demonstrate several examples that explore these techniques in an effort to assess patient-specific biomechanics and predict clinical adverse events associated with mitral and aortic valve diseases. We expect that further advancements in this field will provide clinicians and valve engineers with a wealth of information not otherwise available, and will pave the way for better clinical diagnostics and treatments.

报告人简介

Associate Professor, The Wallace H. Coulter Department of Biomedical Engineering

Georgia Institute of Technology, Atlanta, GA

Dr. Sun is currently an Associate Professor in the Wallace H. Coulter Department of Biomedical Engineering at the Georgia Tech. Dr. Sun received his Ph.D. in 2003 from the Bioengineering Department of the University of Pittsburgh. Before joining Georgia Tech in 2013, he was an Associate Professor in Biomedical Engineering and Mechanical Engineering at the University of Connecticut. His research focuses on the experimental study and constitutive modeling of cardiovascular biomaterials, and the study of tissue and organ function using computational biomechanics tools. His research has been mainly funded by NIH and AHA. He is a Fellow of AHA.

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