报告内容摘要：

Human vitreous is a gelatinous substance that is predominantly composed of collagen fibril, hyaluronic acid (HA) and water. Vitreous substitutes are needed to tamponade the detached retina after vitrectomy when treating retinal detachments. However, several drawbacks associated with current vitreous substitutes have been reported In the present study, we developed a colorless, transparent and injectable hydrogel as a vitreous substitute that was formed by oxidated HA (oxi-HA) and adipic acid dihydrazide (ADH). The biocompatibility was evaluated on a retina pigmented epithelium cell culture by ISO 10993-5, and the hydrogel was found to be nontoxic. This study suggested that the injectable oxi-HA/ADH hydrogel could fulfill many critical elements that are desirable in vitreous substitutes.

报告人简介：

 Feng Huei Lin, Distinguished professor in National Taipei University, Chair professor in National Taipei University of Technology, Executive editor of Journal of Biomedical Engineering (SCI) and International Fellow of International College of Biomaterials Sciences and Engineering.

Dr Lin served as standing committee member in many international societies since 1996. He was permanent international advisory board in Ceramic, Cell and Tissue (CCT) (1998-2010); and served as the President in 2010. He was one of the standing committee members in WACBE (2005-) and council member in TERMIS-AP Chapter (2009-2011). He also served as editorial board members in many SCI journals, for instance, Biomaterials, International Journal of Biomaterials, International Journal of Biomater Resear and Eng, Journal of Musculoskeletal Research etc..

Since 1990, Dr Lin has published over 350 SCI papers, joined 9 book chapters, awarded 47 patents and transferred 14 technologies to industry to be product.