报告内容摘要：

Nuclei acid drugs, especially small interfering RNA (siRNA), can specifically modulate gene expression and promising as targeted therapeutic agents for human diseases. However, there is a substantial barrier to their clinical application due to the need for better delivery system. Liposomes and polymers are very promising carriers for siRNA delivery, but they have many drawbacks, such as poor stability, relatively lower encapsulation efficiency et al. Therefore, we have developed several functional lipid and polymer-based nanoparticles as carriers for siRNA delivery to overcome the disadvantages mentioned above. In the talk, I will share with you the design, synthesis and application of polymer-based biomaterials in terms of siRNA delivery.    

报告人简介：

2004年于天津大学材料学院完成本硕学业后，赴法国斯特拉斯堡大学药学院攻读博士学位，毕业后受邀在法国国家健康与医学研究院任助理研究员。现任中科院过程工程所生物剂型研究部副主任。2010年入选百人计划，2015年获得国家优秀青年基金资助。2014年受邀担任国际诊疗领域权威期刊Theranostics（影响因子为8.8）编委（中国区唯一女性编委）。2015年至今担任中国生物材料学会青年委员会第一届委员、纳米生物材料分会第一届委员，广东省组织工程与再生医学重点实验室学术委员会委员，中国生物医学工程学会纳米医学分会委员，中国机械工程学会表面工程分会生物材料表面工程专委会委员。在国际重要学术期刊（如Advanced Materials, Nano Letters, Biomaterials等）发表论文30余篇。其中近5年以通讯作者发表影响因子大于8的SCI论文15篇，论文被Chemical Society Review等期刊他引700余次，单篇他引最高近150次，撰写中英文书籍章节各1章。

欢迎广大老师和同学们参加！