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Cell-Cycle Specific Anticancer Mechanisms of Chinese Medicinal Mushrooms and Dietary lipids: Flow Cytometric Analyses



主   办:能源与资源工程系
报告人:Jennifer Man-Fan Wan (Associate Professor, The University of Hong Kong)
时   间:3月6日(周一)下午1:00-2:00
地   点:澳门太阳娱乐网站官网1号楼210会议室
主持人:陈峰 教授


报告内容摘要:


Unhealthy diets and lifestyle are known determinants for the leading risk of cancer and death globally. The present talk aims to discuss the cancer preventive mechanisms of natural products, specifically, the Chinese medicinal Mushrooms and Dietary lipids.

She will present her findings to show the anticancer and immunological mechanisms of the polysaccharides peptide (PSP) isolated from the Chinese Medicinal Mushroom “Yun Zhi” from Coriolus versicolor on human leukemic cells. Their data points to the S-phase cell cycle specific mechanism of PSP as well as its specific impacts on the Th1 and Th2 cytokines capable of balances the human T-lymphocytes homeostasis. The anticancer mechanisms diet high in omega-3 polyunsaturated fatty acids and omega-9 monunsaturated fatty acids in animal models will also be discussed.

 
报告人简介:


Dr. Jennifer Wan
Associate Professor
School of Biological Sciences
The University of Hong Kong
Hong Kong, SAR
jmfwan@hku.hk
    Dr. Jennifer Wan, an Associate Professor at the School of Biological Sciences, The University of Hong Kong, has obtained her Bsc degree from the University of London in 1983 and received her doctoral degree in 1987 from the University of Southampton, in England.  Dr. Wan worked as Research Associate at the department of Surgery and later on at the department of Medicine of the Harvard Medicine School, Boston, and USA for more than 7 years. Since 1993, Dr Jennifer Wan has been engaged in teaching and research in nutrition and public health, diet and disease and food science at the University of Hong Kong. But her real passion is on the promotion of research and development of Traditional Chinese Medicine (TCM) to the West. In 2003, Dr. Jennifer Wan has decided to get her second Bsc degree, in Traditional Chinese Medicine (TCM), from the Traditional Chinese Medicine of the University of Beijing, China.  Since then, Dr Wan has applied flow cytometry technology for cancer and immunity research and the “Omics” technology for biomarkers discovery and mechanistic pathways identification on both the principles and applications of TCM. She is the author and co-author of over 80 articles in international journals, book chapters and has supervised more than 20 research postgraduate students. She is proactive in both Teaching and Research in Chinese Medicine.